Journal: Clinical and Translational Radiation Oncology
Article Title: Monitoring glioblastoma dynamics during chemoradiation on the 1.5 T magnetic resonance imaging-linear accelerator
doi: 10.1016/j.ctro.2026.101200
Figure Lengend Snippet: Representative axial (A-C) and sagittal (C) FLAIR images from three patients at fraction 0 (F0), fraction 15 (F15), fraction 30 (F30), and 1 month post-radiotherapy (PM1; diagnostic MRI), demonstrating patient-specific changes in T2/FLAIR region-of-interest (ROI) volume (V), percentage change in V relative to F0 (V rel ), and migration distance (d migrate ). The baseline ROI at F0 is outlined in pink; ROIs at F15, F30, and PM1 are outlined in dark blue. (A) Unmethylated tumor following gross total resection (GTR), without early progression, showing decreasing ROI volume with low d migrate across timepoints. (B) Unmethylated tumor following subtotal resection (STR), with early progression, showing increasing ROI volume with increasing d migrate across timepoints. (C) Methylated tumor following STR, without early progression, showing decreasing ROI volume with large d migrate across timepoints. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
Article Snippet: For radiotherapy planning, all patients underwent MR simulation on a 1.5 T MRI scanner (Philips Ingenia) with gadolinium-enhanced T1-weighted, T2-weighted, diffusion-weight imaging (DWI), and fluid-attenuated inversion recovery (FLAIR) volumetric sequences.
Techniques: Diagnostic Assay, Migration, Methylation